BDBM50104714 CHEMBL109861::N-[5-(4-Chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-2-(thiophene-2-sulfonylamino)-propionamide

SMILES C[C@H](NS(=O)(=O)c1cccs1)C(=O)NC1=NN=C(CS1)c1ccc(Cl)cc1

InChI Key InChIKey=BTMGFNYLYGWAKT-JTQLQIEISA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50104714   

TargetNeutrophil collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104714(CHEMBL109861 | N-[5-(4-Chloro-phenyl)-6H-[1,3,4]th...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104714(CHEMBL109861 | N-[5-(4-Chloro-phenyl)-6H-[1,3,4]th...)
Affinity DataKi:  250nMAssay Description:In vitro inhibitory activity against the catalytic domain of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104714(CHEMBL109861 | N-[5-(4-Chloro-phenyl)-6H-[1,3,4]th...)
Affinity DataKi:  360nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104714(CHEMBL109861 | N-[5-(4-Chloro-phenyl)-6H-[1,3,4]th...)
Affinity DataKi:  550nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104714(CHEMBL109861 | N-[5-(4-Chloro-phenyl)-6H-[1,3,4]th...)
Affinity DataKi:  800nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104714(CHEMBL109861 | N-[5-(4-Chloro-phenyl)-6H-[1,3,4]th...)
Affinity DataKi:  1.04E+3nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104714(CHEMBL109861 | N-[5-(4-Chloro-phenyl)-6H-[1,3,4]th...)
Affinity DataKi:  3.81E+3nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed