BDBM50104716 (R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-thiadiazin-2-yl)propanamide::2-Benzenesulfonylamino-N-(5-p-tolyl-6H-[1,3,4]thiadiazin-2-yl)-propionamide::CHEMBL109214

SMILES C[C@@H](NS(=O)(=O)c1ccccc1)C(=O)NC1=NN=C(CS1)c1ccc(C)cc1

InChI Key InChIKey=PDKBAEDNMKVROV-CQSZACIVSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50104716   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  89nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  90nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  150nMAssay Description:In vitro inhibitory activity against the ectodomain of the human matrix metalloproteinase-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  210nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  220nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  290nMAssay Description:In vitro inhibitory activity against the catalytic domain of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  320nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  440nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104716((R)-2-(phenylsulfonamido)-N-(5-p-tolyl-6H-1,3,4-th...)
Affinity DataKi:  460nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed