BDBM50104719 (S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl)-3-methyl-2-(phenylsulfonamido)butanamide::2-Benzenesulfonylamino-N-[5-(4-chloro-phenyl)-6H-[1,3,4]thiadiazin-2-yl]-3-methyl-butyramide::CHEMBL109603

SMILES CC(C)[C@H](NS(=O)(=O)c1ccccc1)C(=O)NC1=NN=C(CS1)c1ccc(Cl)cc1

InChI Key InChIKey=JOKZNFFZUNYVMR-SFHVURJKSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50104719   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104719((S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl...)
Affinity DataKi:  200nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104719((S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl...)
Affinity DataKi:  380nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104719((S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl...)
Affinity DataKi:  380nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104719((S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl...)
Affinity DataKi:  740nMAssay Description:In vitro inhibitory activity against the catalytic domain of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104719((S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl...)
Affinity DataKi:  780nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104719((S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl...)
Affinity DataKi:  880nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104719((S)-N-(5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl...)
Affinity DataKi: >1.50E+4nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed