BDBM50104842 CHEMBL297962::N-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-dimethyl-cyclopropanecarbonyl]-guanidine::N-[3-(3-Chloro-phenyl)-2,2-dimethyl-cyclopropanecarbonyl]-guanidine
SMILES CC1(C)[C@@H]([C@H]1c1cccc(Cl)c1)C(=O)NC(N)=N
InChI Key InChIKey=VOXCDGBLOPXWPI-ZJUUUORDSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50104842
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform.More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair