BDBM50105033 CHEMBL112531::N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-4-tert-butyl-benzenesulfonamide
SMILES Cc1ccc(cc1)-c1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCOc1ncc(Br)cn1
InChI Key InChIKey=XCDYCRJUBJSYLD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50105033
Affinity DataKi: 0.00420nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to human GH cells which express endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: <0.00100nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to rat A 10 cells which express endothelin A receptorMore data for this Ligand-Target Pair