BDBM50105070 1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino]-propyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL114280

SMILES Clc1cc2OCOc2cc1CNCCCn1c2ccccc2[nH]c1=O

InChI Key InChIKey=PXWAOPCHLIOXQZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50105070   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  3.33E+3nMAssay Description:Inhibition of ligand binding to human delta opioid receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  174nMAssay Description:Inhibition of alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  3.33E+3nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  235nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  328nMAssay Description:Inhibition of sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  507nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  235nMAssay Description:Binding affinity against mu opiate receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  429nMAssay Description:Inhibition of human dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105070(1-{3-[(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-amino...)
Affinity DataIC50:  507nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed