BDBM50105156 4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-thieno[2,3-c]pyridine-2-carboxylic acid methylamide::CHEMBL117279

SMILES CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1

InChI Key InChIKey=RUTWUYYXKRJIPS-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50105156   

TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory potency compared to PMA induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory potency compared to PMA induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Intercellular adhesion molecule-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced Selectin E in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed