BDBM50105447 2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-benzenesulfonyl)-propionamide::CHEMBL90762

SMILES CC(N)(CS(=O)(=O)c1ccc(Sc2ccccc2)cc1)C(=O)NO

InChI Key InChIKey=HXBXLCOXHVGSLM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105447   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed