BDBM50105449 CHEMBL419315::N-[1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl)-1-phenyl-ethyl]-benzamide

SMILES ONC(=O)C(CS(=O)(=O)c1ccc(Oc2ccccc2)cc1)(NC(=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=AWEAPFWTHDDCFJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105449   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105449(CHEMBL419315 | N-[1-Hydroxycarbamoyl-2-(4-phenoxy-...)
Affinity DataIC50:  184nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105449(CHEMBL419315 | N-[1-Hydroxycarbamoyl-2-(4-phenoxy-...)
Affinity DataIC50:  184nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105449(CHEMBL419315 | N-[1-Hydroxycarbamoyl-2-(4-phenoxy-...)
Affinity DataIC50:  161nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105449(CHEMBL419315 | N-[1-Hydroxycarbamoyl-2-(4-phenoxy-...)
Affinity DataIC50:  184nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105449(CHEMBL419315 | N-[1-Hydroxycarbamoyl-2-(4-phenoxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed