BDBM50105454 2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-benzenesulfonyl)-propionamide::CHEMBL329659

SMILES CC(=O)NC(C)(CS(=O)(=O)c1ccc(Sc2ccccc2)cc1)C(=O)NO

InChI Key InChIKey=JSZJOMOAWAHHBK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105454   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105454(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfan...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105454(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfan...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105454(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfan...)
Affinity DataIC50:  580nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50105454(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfan...)
Affinity DataIC50:  540nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105454(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfan...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed