BDBM50105604 5-tert-Butyl-3-[3-(5-tert-butyl-[1,3,4]thiadiazol-2-yl)-ureido]-thiophene-2-carboxylic acid methyl ester::CHEMBL92721::methyl 5-tert-butyl-3-(3-(5-tert-butyl-1,3,4-thiadiazol-2-yl)ureido)thiophene-2-carboxylate

SMILES COC(=O)c1sc(cc1NC(=O)Nc1nnc(s1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=PIAZOLWGBBDPNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105604   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105604(5-tert-Butyl-3-[3-(5-tert-butyl-[1,3,4]thiadiazol-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105604(5-tert-Butyl-3-[3-(5-tert-butyl-[1,3,4]thiadiazol-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105604(5-tert-Butyl-3-[3-(5-tert-butyl-[1,3,4]thiadiazol-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed