BDBM50105614 5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrrol-3-yl)-ureido]-thiophene-2-carboxylic acid methyl ester::CHEMBL93185::methyl 5-tert-butyl-3-(3-(1-isopropyl-1H-pyrrol-3-yl)ureido)thiophene-2-carboxylate

SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccn(c1)C(C)C)C(C)(C)C

InChI Key InChIKey=WBQJSHGQVULOKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50105614   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105614(5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrrol-3-yl)-ure...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105614(5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrrol-3-yl)-ure...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed