BDBM50105618 1-(5-tert-butyl-2-(dimethylcarbamoyl)thiophen-3-yl)-3-p-tolylurea::5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid dimethylamide::5-tert-butyl-N,N-dimethyl-3-(3-p-tolylureido)thiophene-2-carboxamide::CHEMBL94156

SMILES CN(C)C(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C

InChI Key InChIKey=RALWYNSHHMYKBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105618   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105618(1-(5-tert-butyl-2-(dimethylcarbamoyl)thiophen-3-yl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105618(1-(5-tert-butyl-2-(dimethylcarbamoyl)thiophen-3-yl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105618(1-(5-tert-butyl-2-(dimethylcarbamoyl)thiophen-3-yl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed