BDBM50105819 4-Amino-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide::CHEMBL120825

SMILES Nc1ccc(cc1)S(=O)(=O)N(CCCO)c1ccnn1-c1ccccc1

InChI Key InChIKey=CITJDWIHQHOAFD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105819   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50105819(4-Amino-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C9 expressed in yeast strainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50105819(4-Amino-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C19 expressed in yeast strainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50105819(4-Amino-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory effect on human recombinant liver Cytochrome P450 2C8 expressed in yeast strainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C18(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50105819(4-Amino-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed