BDBM50106240 6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-carboxamidine::CHEMBL339902

SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O

InChI Key InChIKey=FEKRWNWZMOSVBX-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106240   

TargetSerine protease hepsin(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50106240(6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed