BDBM50106871 CHEMBL3601368
SMILES CC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCNC(=S)NCCC(O)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(C)=O)C(N)=O
InChI Key InChIKey=AOPLFGKQFHZAKV-VABKMULXSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50106871
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 2.40E+6nMAssay Description:Inhibition of human SIRT6 using H2N-EALPK-(Nepsilon-myristoyl-lysine)-TGGPQ-CONH2 as substrate after 12 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair