BDBM50107120 (E) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-(3-isobutyl-5-methyl-hexylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester::(E)-2-(2-(hydroxymethyl)-4-(3-isobutyl-5-methylhexylidene)-5-oxo-tetrahydrofuran-2-yl)ethyl pivalate::2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-(3-isobutyl-5-methyl-hexylidene)-5-oxo-tetrahydro-furan-2-ylmethyl ester::2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-[3-isobutyl-5-methyl-hex-(E)-ylidene]-5-oxo-tetrahydro-furan-2-ylmethyl ester::CHEMBL137386

SMILES CC(C)CC(C\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O)CC(C)C

InChI Key InChIKey=XKEOGEXDEKIDNA-GIJQJNRQSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50107120   

TargetProtein kinase C epsilon type(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50107120((E) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  1nMAssay Description:Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCepsilon (unknown origin) in presence of 100 ug/ml 100% phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50107120((E) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCepsilon (unknown origin) in presence of nuclear membrane mimetic lipid mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50107120((E) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [20-3H]-PDBU ligand from recombinant protein kinase C (baculovirus)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50107120((E) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCalpha (unknown origin) in presence of 100 ug/ml 100% phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50107120((E) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  46nMAssay Description:Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCalpha (unknown origin) in presence of nuclear membrane mimetic lipid mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed