BDBM50107160 1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-3-trifluoromethyl-phenyl]-propenone::CHEMBL138777

SMILES CC(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Sc2ccc3OCCOc3c2)c(c1)C(F)(F)F

InChI Key InChIKey=WZKOECKNEHAVJL-XVNBXDOJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107160   

TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107160(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benz...)
Affinity DataIC50:  55nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(50-60)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107160(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2,3-dihydro-benz...)
Affinity DataIC50:  60nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (30-170)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed