BDBM50107161 1-(4-Acetyl-piperazin-1-yl)-3-[2,3-dichloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-phenyl]-propenone::CHEMBL341999

SMILES CC(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Sc2ccc3OCCOc3c2)c(Cl)c1Cl

InChI Key InChIKey=GYELUVCNTNLZSS-XVNBXDOJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107161   

TargetIntegrin alpha-L(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107161(1-(4-Acetyl-piperazin-1-yl)-3-[2,3-dichloro-4-(2,3...)
Affinity DataIC50:  7nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(6-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107161(1-(4-Acetyl-piperazin-1-yl)-3-[2,3-dichloro-4-(2,3...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (6-10)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed