BDBM50107560 CHEMBL354528::N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-5-(2-methoxy-phenoxy)-2-(4-methyl-piperazin-1-yl)-pyrimidin-4-yl]-4-tert-butyl-benzenesulfonamide

SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOc1ncc(Br)cn1)N1CCN(C)CC1

InChI Key InChIKey=NMHKNNATZNLGSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107560   

TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107560(CHEMBL354528 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.450nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed