BDBM50107991 6-[(3-Fluoro-4-methoxy-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL356620

SMILES COc1ccc(NCc2cnc3nc(N)nc(N)c3c2C)cc1F

InChI Key InChIKey=AQQUQMYXZNSCJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107991   

TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107991(6-[(3-Fluoro-4-methoxy-phenylamino)-methyl]-5-meth...)
Affinity DataIC50:  14nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107991(6-[(3-Fluoro-4-methoxy-phenylamino)-methyl]-5-meth...)
Affinity DataIC50:  0.910nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed