BDBM50108086 CHEMBL3601072::US9598440, 66

SMILES CN(C)c1ccc(Nc2ncc(-c3nc4cnccc4s3)c(N[C@@H]3C[C@H](CO)[C@@H](O)[C@H]3O)n2)cc1

InChI Key InChIKey=AVTABSHKAQXPLX-PUZMVAROSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108086   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50108086(CHEMBL3601072 | US9598440, 66)
Affinity DataIC50:  4nMAssay Description:Procedure: A 20 μl reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (R...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50108086(CHEMBL3601072 | US9598440, 66)
Affinity DataIC50:  4nMAssay Description:Inhibition of human IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed