BDBM50108176 4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-phenoxy]-butyric acid::CHEMBL37696
SMILES COc1ccc(OCCCC(O)=O)cc1Cc1cnc(N)nc1N
InChI Key InChIKey=NNYBKFNWRMTXCR-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50108176
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase (DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase (DHFR) of ratMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase (DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase (DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair