BDBM50108179 9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-phenoxy]-nonanoic acid::CHEMBL38332

SMILES COc1ccc(OCCCCCCCCC(O)=O)cc1Cc1cnc(N)nc1N

InChI Key InChIKey=GWFSIQAFBODUBN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108179   

TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50:  4.80E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50:  430nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108179(9-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed