BDBM50108195 3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromethyl-benzenesulfonylamino)-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL276982

SMILES Cn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O

InChI Key InChIKey=WYPXYGWFNRNTHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108195   

TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)
Affinity DataIC50:  228nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)
Affinity DataIC50:  6.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed