BDBM50108197 3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-2-oxo-ethyl)-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL24015

SMILES Cn1cc(C(C(=O)NS(=O)(=O)c2ccccc2)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O

InChI Key InChIKey=QYBAEPJHJXGPBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108197   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)
Affinity DataIC50:  2.57E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed