BDBM50108199 CHEMBL279703::N-[2-(6-Aminomethyl-1-methyl-1H-indol-3-yl)-2-benzo[1,3]dioxol-5-yl-acetyl]-4-isopropyl-benzenesulfonamide

SMILES CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(CN)ccc12)c1ccc2OCOc2c1

InChI Key InChIKey=JGAUQCSCABMOTB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108199   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108199(CHEMBL279703 | N-[2-(6-Aminomethyl-1-methyl-1H-ind...)
Affinity DataIC50:  38nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108199(CHEMBL279703 | N-[2-(6-Aminomethyl-1-methyl-1H-ind...)
Affinity DataIC50:  204nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed