BDBM50108200 3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL433619

SMILES Cn1cc(C(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O

InChI Key InChIKey=UXILKFUTGKEPOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108200   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed