BDBM50108203 3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulfonylamino)-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22249

SMILES Cc1ccccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1

InChI Key InChIKey=WKYQABAYTVWYQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108203   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)
Affinity DataIC50:  1.06E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed