BDBM50108295 CHEMBL288817::Indolocarbazole analogue
SMILES COCc1ccc2n3[C@H]4C[C@](O)(C(=O)OC)[C@](C)(O4)n4c5ccc(COC)cc5c5c6CNC(=O)c6c(c2c1)c3c45
InChI Key InChIKey=MDAFGVXLBFQEJH-XCFOVOSNSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50108295
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of NGF high affinity receptor tyrosine kinase TrkAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
TargetProtein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type(Rattus norvegicus)
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair