BDBM50108296 CHEMBL289772::Indolocarbazole analogue

SMILES COC(=O)[C@@]1(O)C[C@H]2O[C@]1(C)n1c3ccc(CO)cc3c3c4CNC(=O)c4c4c5cc(CO)ccc5n2c4c13

InChI Key InChIKey=SIBOQVCECFIQAO-ACVHLROOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108296   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type(Rattus norvegicus)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)
Affinity DataIC50:  15nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed