BDBM50108346 CHEMBL295295::Indole Derivative

SMILES C[C@@H]1C2C3Cc4ccc(O)c5O[C@@H](c6[nH]c7ccccc7c16)C2(CCN3C)c45

InChI Key InChIKey=BKKGVUYVPORNKS-GAQQVJAQSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50108346   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50108346(CHEMBL295295 | Indole Derivative)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for delta opioid receptor by displacing [3H]DADL was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50108346(CHEMBL295295 | Indole Derivative)
Affinity DataKi:  49nMAssay Description:Binding affinity of the compound for gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Niddk

Curated by ChEMBL
LigandPNGBDBM50108346(CHEMBL295295 | Indole Derivative)
Affinity DataKi:  126nMAssay Description:Binding affinity for kappa opioid receptor by displacing [3H]U-69593 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50108346(CHEMBL295295 | Indole Derivative)
Affinity DataKi:  240nMAssay Description:Binding affinity for mu opioid receptor by displacing [3H]-DAMGO was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Niddk

Curated by ChEMBL
LigandPNGBDBM50108346(CHEMBL295295 | Indole Derivative)
Affinity DataKi:  398nMAssay Description:Binding affinity of the compound for kappa opioid receptor by displacing U-69,593 was determined in [35S]-GTP gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Niddk

Curated by ChEMBL
LigandPNGBDBM50108346(CHEMBL295295 | Indole Derivative)
Affinity DataKi: >600nMAssay Description:Binding affinity of the compound for mu opioid receptor by displacing DAMGO was determined in [35S]-GTP gamma-S binding assay; InactiveMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed