BDBM50109207 8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-benzyl)-6-{[methyl-(2-pyridin-2-yl-ethyl)-amino]-methyl}-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid cyclopentyl ester::CHEMBL131665

SMILES CN(CCc1ccccn1)Cc1c(c(C#N)c2n(Cc3ccccc3F)cc(C(=O)OC3CCCC3)c(=O)n12)-c1ccc(OC2CCCC2)cc1

InChI Key InChIKey=BJIUDYSNIPRIDK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109207   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50109207(8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...)
Affinity DataKi:  33nMAssay Description:Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50109207(8-Cyano-7-(4-cyclopentyloxy-phenyl)-1-(2-fluoro-be...)
Affinity DataKi:  8.90E+3nMAssay Description:Binding affinity of the compound against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed