BDBM50109219 4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide::CHEMBL339636

SMILES Cc1cc(cc(C)c1C)-c1c(OCC[C@@H]2CCN2)c2cc(ccc2[nH]c1=O)C(=O)Nc1ccncn1

InChI Key InChIKey=ORQDFXXLMSCLDY-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109219   

TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50109219(4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...)
Affinity DataIC50:  4nMAssay Description:Binding affinity of the compound against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50109219(4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against human GnRH receptor of the compound using des-Gly10[125I-Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed