BDBM50109475 1-(benzo[d][1,3]dioxol-5-yl)-3-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::CHEMBL165083

SMILES CCn1cc2c(n1)nc(NC(=O)Nc1ccc3OCOc3c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=FVFSYIHQKDNCSO-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50109475   

TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]MRE3008-F20 from human Adenosine A3 receptor expressed in HEK cells; range 0.22-0.34More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)TBA
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  0.270nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A2B receptor expressed in HEK293 cells; range 37-63More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  576nMAssay Description:Displacement of [3H]SCH-58261 from human Adenosine A2A receptor expressed in HEK293 cells; range 511-648More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  576nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109475(1-Benzo[1,3]dioxol-5-yl-3-(8-ethyl-2-furan-2-yl-8H...)
Affinity DataKi:  802nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 724-889More data for this Ligand-Target Pair
In DepthDetails Article
PubMed