BDBM50109624 (6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL173316

SMILES CCOP(=O)(N1Cc2ccsc2CC1C(=O)NO)c1ccc(OC)cc1

InChI Key InChIKey=CDUNTBSHRUTDFM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109624   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109624((6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]py...)
Affinity DataKi:  3.80nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109624((6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]py...)
Affinity DataKi:  4.10nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109624((6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]py...)
Affinity DataKi:  5.20nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109624((6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]py...)
Affinity DataKi:  6.45nMAssay Description:Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109624((6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]py...)
Affinity DataIC50:  520nMAssay Description:Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed