BDBM50110978 8-(4-Bromo-phenyl)-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL286527

SMILES Brc1ccc(cc1)-c1nc2[nH]c(=O)n(CC#C)c(=O)c2[nH]1

InChI Key InChIKey=MZKFWENNHZOFBS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50110978   

TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50110978(8-(4-Bromo-phenyl)-1-prop-2-ynyl-3,7-dihydro-purin...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of [3H]-ZM-241,385 binding to human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50110978(8-(4-Bromo-phenyl)-1-prop-2-ynyl-3,7-dihydro-purin...)
Affinity DataKi:  60nMAssay Description:Inhibition of [3H]-CCPA binding to rat adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50110978(8-(4-Bromo-phenyl)-1-prop-2-ynyl-3,7-dihydro-purin...)
Affinity DataKi:  199nMAssay Description:Inhibition of [3H]-MSX-2 binding to rat adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50110978(8-(4-Bromo-phenyl)-1-prop-2-ynyl-3,7-dihydro-purin...)
Affinity DataKi:  477nMAssay Description:Inhibition of [3H]-PSB-11 binding to human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed