BDBM50111025 9-[1-Thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricyclo[4.3.1.0*3,7*]decane-2-carboxylic acid methyl ester::CHEMBL331565

SMILES COC(=O)C1C2CCC3CC1\C(CN23)=C\c1cccs1

InChI Key InChIKey=ZLWKHMNSEAGVBX-JXMROGBWSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50111025   

TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111025(9-[1-Thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricycl...)
Affinity DataKi:  26nMAssay Description:Ability to inhibit reuptake of norepinephrine ([3H]NE) at norepinephrine transporter of rat parietal/occipital regionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111025(9-[1-Thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricycl...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]-NE reuptake at Norepinephrine transporter in rat parietal/occipital cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111025(9-[1-Thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricycl...)
Affinity DataKi:  268nMAssay Description:Ability to inhibit reuptake of dopamine ([3H]DA) at dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111025(9-[1-Thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricycl...)
Affinity DataKi:  268nMAssay Description:Inhibition of [3H]DA reuptake at dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111025(9-[1-Thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricycl...)
Affinity DataKi:  2.05E+3nMAssay Description:Inhibition of [3H]5-HT reuptake at serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111025(9-[1-Thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricycl...)
Affinity DataKi:  2.05E+3nMAssay Description:Ability to inhibit reuptake of serotonin ([3H]5-HT) at serotonin transporter of rat midbrianMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed