BDBM50111320 CHEMBL274096::N'-(10-Methoxy-13H-5,13-diaza-dibenzo[a,i]fluoren-6-yl)-N,N-dimethyl-propane-1,3-diamine

SMILES COc1ccc2c3[nH]c4c(c(NCCCN(C)C)nc5ccccc45)c3ccc2c1

InChI Key InChIKey=GDEUZHXVKFARAU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111320   

TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111320(CHEMBL274096 | N'-(10-Methoxy-13H-5,13-diaza-diben...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for inhibitory activity against Telomerase in telomerase repeat amplification protocol (TRAP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111320(CHEMBL274096 | N'-(10-Methoxy-13H-5,13-diaza-diben...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111320(CHEMBL274096 | N'-(10-Methoxy-13H-5,13-diaza-diben...)
Affinity DataIC50:  1.00E+9nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA polymerase I, thermostable(Thermus aquaticus)
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111320(CHEMBL274096 | N'-(10-Methoxy-13H-5,13-diaza-diben...)
Affinity DataIC50:  900nMAssay Description:Tested for inhibitory activity against Taq DNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed