BDBM50112505 4-Hydroxy-3-{3-[4-(1-methyl-piperidin-4-yloxy)-3-trifluoromethyl-phenylamino]-propenyl}-benzamidine::CHEMBL24956

SMILES CN1CCC(CC1)Oc1ccc(NC\C=C\c2cc(ccc2O)C(N)=N)cc1C(F)(F)F

InChI Key InChIKey=RUYKLYHEIHLGDA-NSCUHMNNSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112505   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112505(4-Hydroxy-3-{3-[4-(1-methyl-piperidin-4-yloxy)-3-t...)
Affinity DataKi:  0.580nMAssay Description:Competitive inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112505(4-Hydroxy-3-{3-[4-(1-methyl-piperidin-4-yloxy)-3-t...)
Affinity DataKi:  630nMAssay Description:Competitive inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112505(4-Hydroxy-3-{3-[4-(1-methyl-piperidin-4-yloxy)-3-t...)
Affinity DataKi:  1.82E+3nMAssay Description:Competitive inhibition of coagulation factor IIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed