BDBM50113510 CHEMBL3604656

SMILES CC(C)S(=O)(=O)c1nn(C)cc1Nc1nc(Nc2cc(C)c(cc2OC2CC2)C2CCCN(C)C2)ncc1Cl

InChI Key InChIKey=ZMHAGOARORDFHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113510   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113510(CHEMBL3604656)
Affinity DataIC50:  3nMAssay Description:Inhibition of wild type human recombinant ALK using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113510(CHEMBL3604656)
Affinity DataIC50:  7nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed