BDBM50113667 4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-benzamide::CHEMBL77665

SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)c2ccc(OCc3ccccc3)cc2)cc1

InChI Key InChIKey=CKNATELLDRWWKR-MHZLTWQESA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50113667   

TargetCathepsin K(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataKi:  15nMAssay Description:Eq. constant (Ki) for inhibition of Cathepsin K was determined by progress curves, following hydrolysis of Z-Phe-Arg- Amc in the absence and presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant human cathepsin S in a fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human cathepsin L in a fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113667(4-Benzyloxy-N-{1-[2-(4-methoxy-phenylamino)-ethylc...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human cathepsin K in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed