BDBM50114250 1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-(4-pyridin-4-ylmethyl-phenyl)-urea::CHEMBL288812
SMILES Cn1nc(cc1NC(=O)Nc1ccc(Cc2ccncc2)cc1)C(C)(C)C
InChI Key InChIKey=FRQKYYNHZICJDA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50114250
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Novartis Research Foundation
Curated by ChEMBL
Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bayer Research Center
Curated by ChEMBL
Bayer Research Center
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human epidermal growth factor receptor-2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Novartis Research Foundation
Curated by ChEMBL
Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair