BDBM50114943 (2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-1-aza-bicyclo[2.2.2]octane::CHEMBL50270

SMILES FC(F)(F)c1cc(CO[C@H]2C3CCN(CC3)[C@H]2c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=CJUCQSBUIKQBDX-PMACEKPBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114943   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114943((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)
Affinity DataIC50:  0.200nMAssay Description:Tested for inhibitory concentration expressed as displacement of [125I]-labeled substance P from the cloned human Tachykinin receptor 1 expressed in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed