BDBM50114946 4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cyclohexanecarboxylic acid 3,5-bis-trifluoromethyl-benzyl ester::CHEMBL295735

SMILES Fc1ccc(cc1)C1CCN(CC1)C1CCC(CC1)(C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=SPOQEIILUHGCDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114946   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114946(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50:  140nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50114946(4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cy...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed