BDBM50114997 4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3H-thiazol-(2E)-ylideneamine::CHEMBL48892

SMILES Cc1cc(ccc1Cl)-c1csc(=N)n1-c1ccc(Cl)cc1

InChI Key InChIKey=WWICDNHPMVBSRN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114997   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114997(4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...)
Affinity DataKi:  24nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114997(4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...)
Affinity DataKi:  24nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114997(4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...)
Affinity DataKi:  99nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50114997(4-(4-Chloro-3-methyl-phenyl)-3-(4-chloro-phenyl)-3...)
Affinity DataKi:  225nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed