BDBM50115005 4-(4-Chloro-phenyl)-3-(2-fluoro-phenyl)-3H-thiazol-(2Z)-ylideneamine::CHEMBL49736

SMILES Fc1ccccc1-n1c(csc1=N)-c1ccc(Cl)cc1

InChI Key InChIKey=SZTWXAFPFTWJHZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115005   

TargetTransporter(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50115005(4-(4-Chloro-phenyl)-3-(2-fluoro-phenyl)-3H-thiazol...)
Affinity DataKi:  36nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50115005(4-(4-Chloro-phenyl)-3-(2-fluoro-phenyl)-3H-thiazol...)
Affinity DataKi:  189nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50115005(4-(4-Chloro-phenyl)-3-(2-fluoro-phenyl)-3H-thiazol...)
Affinity DataKi:  1.41E+3nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed