BDBM50115115 (Cyclohexylamino-phosphono-methyl)-phosphonic acid::(cyclohexylamino)methylenediphosphonic acid::CHEMBL56253::[(cyclohexylamino)methylene]-1,1-bisphosphonate
SMILES OP(O)(O)C(=NC1CCCCC1)P(O)(O)=O
InChI Key InChIKey=WVRLNRXGOAYRFR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50115115
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 62.4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 366nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
TargetPolyprenyl synthetase family protein(Plasmodium falciparum (isolate 3D7))
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 61.1nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair