BDBM50115150 2-Amino-6-methylaminomethyl-5,6,7,8-tetrahydro-3H-pteridin-4-one::CHEMBL420453

SMILES CNCC1CNc2nc(N)[nH]c(=O)c2N1

InChI Key InChIKey=LHIQNSIRCHEIBK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115150   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115150(2-Amino-6-methylaminomethyl-5,6,7,8-tetrahydro-3H-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115150(2-Amino-6-methylaminomethyl-5,6,7,8-tetrahydro-3H-...)
Affinity DataIC50:  4.12E+3nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50115150(2-Amino-6-methylaminomethyl-5,6,7,8-tetrahydro-3H-...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50115150(2-Amino-6-methylaminomethyl-5,6,7,8-tetrahydro-3H-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed