BDBM50115560 4-(4-Chloro-phenyl)-1-(3-fluoro-propyl)-piperidine-3-carboxylic acid methyl ester::CHEMBL108469

SMILES COC(=O)C1CN(CCCF)CC[C@@H]1c1ccc(Cl)cc1

InChI Key InChIKey=ZINIQUUPUINBQU-GICMACPYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115560   

TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115560(4-(4-Chloro-phenyl)-1-(3-fluoro-propyl)-piperidine...)
Affinity DataKi:  335nMAssay Description:Inhibition of high affinity uptake of [3H]NE by norepinephrine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115560(4-(4-Chloro-phenyl)-1-(3-fluoro-propyl)-piperidine...)
Affinity DataKi:  4.28E+3nMAssay Description:Inhibition of high affinity uptake of [3H]-DA by dopamine transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50115560(4-(4-Chloro-phenyl)-1-(3-fluoro-propyl)-piperidine...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of high affinity uptake of [3H]5-HT by serotonin transporter in nerve endings obtained from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed